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47 results

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Page 1
Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors.
Selinger M, Věchtová P, Tykalová H, Ošlejšková P, Rumlová M, Štěrba J, Grubhoffer L. Selinger M, et al. Comput Struct Biotechnol J. 2022 May 30;20:2759-2777. doi: 10.1016/j.csbj.2022.05.052. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35685361 Free PMC article.
Tick-borne encephalitis virus (TBEV), the most medically relevant tick-transmitted flavivirus in Eurasia, targets the host central nervous system and frequently causes severe encephalitis. ...Candidate mechanisms responsible for the aforementioned phenomena include specifi …
Tick-borne encephalitis virus (TBEV), the most medically relevant tick-transmitted flavivirus in Eurasia, targets the host central ne …
Secretory pathways and multiple functions of nonstructural protein 1 in flavivirus infection.
Zhang S, He Y, Wu Z, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Ou X, Gao Q, Sun D, Zhang L, Yu Y, Chen S, Cheng A. Zhang S, et al. Front Immunol. 2023 Jul 13;14:1205002. doi: 10.3389/fimmu.2023.1205002. eCollection 2023. Front Immunol. 2023. PMID: 37520540 Free PMC article. Review.
The genus Flavivirus contains a wide variety of viruses that cause severe disease in humans, including dengue virus, yellow fever virus, Zika virus, West Nile virus, Japanese encephalitis virus and tick-borne encephalitis …
The genus Flavivirus contains a wide variety of viruses that cause severe disease in humans, including dengue virus, yellow fe …
Target specific inhibition of West Nile virus envelope glycoprotein and methyltransferase using phytocompounds: an in silico strategy leveraging molecular docking and dynamics simulation.
Akash S, Bayıl I, Rahman MA, Mukerjee N, Maitra S, Islam MR, Rajkhowa S, Ghosh A, Al-Hussain SA, Zaki MEA, Jaiswal V, Sah S, Barboza JJ, Sah R. Akash S, et al. Front Microbiol. 2023 Jun 28;14:1189786. doi: 10.3389/fmicb.2023.1189786. eCollection 2023. Front Microbiol. 2023. PMID: 37455711 Free PMC article.
Mosquitoes are the primary vector for West Nile virus, a flavivirus. The virus's ability to infiltrate and establish itself in increasing numbers of nations has made it a persistent threat to public health worldwide. ...West Nile
Mosquitoes are the primary vector for West Nile virus, a flavivirus. The virus's ability to infiltrate an …
Matrix metalloproteinase 9 facilitates West Nile virus entry into the brain.
Wang P, Dai J, Bai F, Kong KF, Wong SJ, Montgomery RR, Madri JA, Fikrig E. Wang P, et al. J Virol. 2008 Sep;82(18):8978-85. doi: 10.1128/JVI.00314-08. Epub 2008 Jul 16. J Virol. 2008. PMID: 18632868 Free PMC article.
West Nile virus (WNV) is the most-common cause of mosquito-borne encephalitis in the United States. ...These data suggest that MMP9 plays a role in mediating WNV entry into the central nervous system and that strategies to interrupt this process may influence
West Nile virus (WNV) is the most-common cause of mosquito-borne encephalitis in the United States. ...These data sugge
Reproduction numbers of infectious disease models.
van den Driessche P. van den Driessche P. Infect Dis Model. 2017 Jun 29;2(3):288-303. doi: 10.1016/j.idm.2017.06.002. eCollection 2017 Aug. Infect Dis Model. 2017. PMID: 29928743 Free PMC article. Review.
Beginning with a simple population model, the concept is developed for a threshold value of 0 determining whether or not the disease dies out. The next generation matrix method of calculating 0 in a compartmental model is described and illustrated. ...These theoretical ide …
Beginning with a simple population model, the concept is developed for a threshold value of 0 determining whether or not the disease dies ou …
Matrix-M adjuvanted envelope protein vaccine protects against lethal lineage 1 and 2 West Nile virus infection in mice.
Magnusson SE, Karlsson KH, Reimer JM, Corbach-Söhle S, Patel S, Richner JM, Nowotny N, Barzon L, Bengtsson KL, Ulbert S, Diamond MS, Stertman L. Magnusson SE, et al. Vaccine. 2014 Feb 7;32(7):800-8. doi: 10.1016/j.vaccine.2013.12.030. Epub 2013 Dec 28. Vaccine. 2014. PMID: 24380682
West Nile virus (WNV) is a mosquito-transmitted flavivirus and an emerging pathogen in many parts of the world. ...Importantly, mice vaccinated with Matrix-M formulated E protein were protected from lethal challenge with both lineage 1 and 2 WNV strain
West Nile virus (WNV) is a mosquito-transmitted flavivirus and an emerging pathogen in many parts of the world. ...Impo
Signaling events evoked by domain III of envelop glycoprotein of tick-borne encephalitis virus and West Nile virus in human brain microvascular endothelial cells.
Bhide K, Mochnáčová E, Tkáčová Z, Petroušková P, Kulkarni A, Bhide M. Bhide K, et al. Sci Rep. 2022 May 25;12(1):8863. doi: 10.1038/s41598-022-13043-1. Sci Rep. 2022. PMID: 35614140 Free PMC article.
Tick-borne encephalitis virus and West Nile virus can cross the blood-brain barrier via hematogenous route. ...Furthermore, both cases showed dramatic dysregulation of IFN and IFN-induced genes. Results strongly suggest that the virus contact to …
Tick-borne encephalitis virus and West Nile virus can cross the blood-brain barrier via hematogenous route. ...F …
Structure of West Nile virus.
Mukhopadhyay S, Kim BS, Chipman PR, Rossmann MG, Kuhn RJ. Mukhopadhyay S, et al. Science. 2003 Oct 10;302(5643):248. doi: 10.1126/science.1089316. Science. 2003. PMID: 14551429 No abstract available.
Development of a Multivalent Kunjin Virus Reporter Virus-Like Particle System Inducing Seroconversion for Ebola and West Nile Virus Proteins in Mice.
Tran PT, Asghar N, Höglund U, Larsson O, Haag L, Mirazimi A, Johansson M, Melik W. Tran PT, et al. Microorganisms. 2020 Nov 29;8(12):1890. doi: 10.3390/microorganisms8121890. Microorganisms. 2020. PMID: 33260425 Free PMC article.
Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile virus (WNV). ...In this study, we aimed to develop a system to generate multivalent RVPs based on KUNV to elicit an immune response against different viruses. We sel …
Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile virus (WNV). ...In this study, w …
West Nile virus-induced disruption of the blood-brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases.
Roe K, Kumar M, Lum S, Orillo B, Nerurkar VR, Verma S. Roe K, et al. J Gen Virol. 2012 Jun;93(Pt 6):1193-1203. doi: 10.1099/vir.0.040899-0. Epub 2012 Mar 7. J Gen Virol. 2012. PMID: 22398316 Free PMC article.
West Nile virus (WNV) encephalitis is characterized by neuroinflammation, neuronal loss and blood-brain barrier (BBB) disruption. ...Herein, we characterized the relationship between the BBB disruption and expression kinetics of key TJP, AJP and matrix
West Nile virus (WNV) encephalitis is characterized by neuroinflammation, neuronal loss and blood-brain barrier (BBB) d
47 results